SUPPLEMENTS FOR LONGEVITY

This article is copyright © Nils Osmar 2020. It’s intended solely for informational purposes. It is not meant to be taken as, and should not be construed, as medical advice. Any changes to your lifestyle or diet should be done in consultation with your doctor or health care professional.  Interested in anti-aging? Check out the Facebook Group –– ANTI-AGING THERAPIES.

  • I don’t take all of the supplements listed below every day. 
  • But I do take some in each category on most days.

Stack 1: NAD Boosters – I start off most weekday mornings with these:


  1. NMN – nicotinamide mononucleotide – shown to raise levels of NAD+ in the body.
  2. Resveratrol and pterostilbene. Both are NAD+ activators.  Should be taken with fat or protein. I take with a bite of avocado.
  3. TMG – Trimethylglycine – replaces the methyl groups that are depleted when the body metabolizes NMN.
  4. PQQ (for mitochondrial biogenesis)
  5. Ubiquinol (goes well with PQQ to support mitochondria)

More details:


  • I’m currently taking six 125 mg. capsules of NMN (nicotinamide mononucleotide) every the morning, along with resveratrol(450 mg) and TMG (1 gram). NMN increases NAD+ levels in the body.
  • Resveratrol activates the NAD produced by the NMN. I feel a major difference when I take them together.
  • TMG restores the methyl groups that are used up when our bodies metabolize NMN.
  • PQQ and ubiquinol support mitochondrial biogenesis.
  • Like Dr. David Sinclair, the Harvard Medical School Professor who has done much of the research related to NMN, I take the supplements above in the morning. Sinclair takes 1 gram per day; I take 750 mg. Then I don’t eat anything else until noon or 1 p.m. 
  • Joe Rogan interviews David Sinclair about NMN

Stack 2: Testosterone boosters


Testosterone is essential to both men and women to maintain muscle mass as we age, and to protect brain health.

I start most mornings with a hot-cold shower (3 minutes hot, 2 minutes cold, 3 minutes hot, 3 minutes cold). This puts a little stress on my mitochondria. After the shower, I do 10 minutes in a red light chamber. Then an hour or so later, I usually take some testosterone-boosters. What I take most days:

  1. Astaxanthin (12 mg)
  2. Saw Palmetto (organic) (200 mg)
  3. Reuteri 6475 (a particular strain of L. Reuteri that increases T levels, supports brain integrity, and fortifies bones) (1 capsule)
  4. Boron (200 mg)
  5. DHEA cream (small dollop on my wrist)

About these supplements: 

  • Astaxanthin and saw palmetto multiply each others’ effect. Taken together, they give T-levels a decided boost.
  • I take them partly for longevity, partly for prostate health, and partly to support high testosterone levels.
  • Astaxanthin taken internally also prevents sunburn, thought it takes a couple of weeks for it to building up to a high enough level in your body to accomplish this. Because I take it, I can get sun exposure without having to smear on toxic, carcinogenic sunscreens.
  • DHEA levels drop as we age, so it be helpful to replace it. But it’s best not to use it every day, or apply it on areas where you have body fat, as it can be accumulate in the fat. I put it on my inner wrists where there’s no body fat.
  • As noted above, I rotate them. I take three of ’em every weekday; take a break from them on the weekends; and take the others when I feel like it.

Stack 3: Other supplements

Supplements that I take once or twice a week include:

  1. Berberine and milk thistle (go well together) (support healthy blood glucose levels) (I sometimes also take cinnamon and chromium for the same reason.)
  2. Multivitamin/mineral with B vitamins – high in B12
  3. Pantethine (for endurance and longevity)
  4. PS (phosphatidyl serine) for brain health
  5. Astragalus  (for telomere health)  (astragalus is an herb used in traditional Chinese medicine, which repairs telomeres) (Note: it should NOT be taken during a prolonged fast)

Stack 4: Nighttime supplements

  1. Calcium/magnesium with vitamin D (supports the production of melatonin by the pineal gland)
  2. Time-release NAC (keeps my breathing clear)