I do INTERMITTENT FASTING (also known as TIME-RESTRICTED EATING) every day, because it decreases insulin; raises HGH (human growth hormone) levels; is good for brain health; helps normalize cholesterol levels and and lower blood triglycerides; and helps keep my weight around where it should be.

  • I usually finish dinner around 6 pm, then “fast” till around noon the following day. 
  • Like David Sinclair, whose regimen I’m trying to approximate, I do sometimes take a bite or two of food around 8 a.m. on days when I’m taking resveratrol, which can’t be absorbed without some fat or protein. And I sometimes put cream in my morning coffee. So a fasting purist would say I’m only fasting for 14 hours (between 6 p.m. and my first bite of food or cup of coffee at 8 a.m.)


  • In addition to my daily 14 hour “fast,”, I do a 4 or 5 day PROLONGED FAST or fasting mimicking diet (FMD) several times a year. 
  • Both prolonged fasts and FMDs have many benefits, including autophagy (cleaning accumulated debris from our cells); apoptosis (the body cannibalizes and destroys senescent cells during a prolonged fast); and the creation of new stem cells at the end of the fast.
  • Daily intermittent fasting (time restricted eating) does not have these benefits. The fast has to be several days long to experience apoptosis.
  • Dr. Longo’s research has shown that prolonged fasts and FMDs produce potent results, including boosting the functioning of the immune system, killing off senescent cells, and triggering stem cell regeneration.
  • One caution: In Dr. Longo’s studies, these benefits were pronounced in young mice, but older mice did not always respond well to fasting. So it’s possible that past a certain age, fasting may not be beneficial in people either. My health has benefited greatly from doing fasts and FMDs in the past, so I’ll keep doing them till I have evidence that they’re not working.