This article is intended solely for informational purposes. It is not meant to be taken as, and should not be construed, as medical advice. Any changes to your lifestyle or diet should be done in consultation with your doctor or health care professional.


My Experience Taking NMN –– How Much I Take, and Why

I started out taking 1 capsule of NMN (125 mg). It had no effect, as far as I could tell.

I then tried taking 2 capsules, then 4, then 6. But I felt like I was flying in the dark.

When I learned about the 8 mg per kg of body weight recommendation, I switched to taking six capsules of NMN per day for a few weeks. Each capsule is 125 mg, so I was getting a total of  750 mg. (Five capsules would only have given me 625 mg, less than I needed according to this study.) 

I can’t quite explain why, but it felt like too much. It may be because I was actually pushing my NAD levels too high (if there is such a thing as having too much NMN), and my body could sense that it was overkill to take that much more. (I do fasting, cold showers and HIIT exercise, all of which increase NAD levels in the body.) (I’m 66 years old at the time I’m writing this, an age at which NAD is naturally declining, so am doing a number of things to try to keep my levels up.)

Whatever the reason, I felt like it was too much, and not just because of the daily hit to my pocketbook.  I cut back to four 125-mg capsules a day, which feels about right to me at the moment.

Taking even this smaller amount can be pricey. NMN supplements from reputable sources cost between 70 cents and a dollar per 125 mg capsule. I bought a bunch on sale, but even at the sale price, it’s costing me $3 a day to take this much NMN (plus the cost of the resveratrol and TMG I’m taking along with it).

Still, it’s less than the cost of taking an entire gram every day. And less than the price of a latte.  And what’s another few years of life and health worth, if it works in the ways many of us are hoping?

Of course, this leads us back to a question which has never really been answered, i.e., is it good for people to be taking NMN at all? I hope it is, but it hasn’t really been proven to be the case.

See also: Why I don’t take NMN sublingually

P.S. The leading researcher who has popularized NMN, Harvard’s Dr. David Sinclair, has not gone on record as recommending any particular doses of these supplements for others. He does not even recommend that everyone take NMN (though he doesn’t recommend avoiding it either).

But he has said in some recent interviews that he thinks that for those who are taking it the typical amount of 250 mg/day is too little to have much of an effect on the aging process in humans.

This dovetails with the answer given by the researchers I’ve quoted in the earlier sections of this article.